Men’s and women’s symptoms differ for the same disease

Men’s and women’s symptoms differ for the same disease

News flash: Men and women are different.

Before you roll your eyes and laugh, this really is a bit of a novel idea—at least in the medical field. You see, for centuries, men and women were treated the same when it came to disease prevention, diagnosis, and management.

But today, we know this approach is flawed. In many cases, the same exact disease not only presents different symptoms in men and women, but the treatment that works for one sex can prove to be totally ineffective for the other.

In no condition is this more evident than heart disease….

Heart Disease

Diseases involving the heart—heart disease, heart attacks, etc.—often present themselves very differently in men versus women. As you might expect, hormones have a lot to do with why.

Estrogen is thought to offer protection against heart disease by keeping blood vessels flexible. That’s why it’s pretty unusual for healthy premenopausal women to suffer from heart disease or a heart attack.

However, with the dramatic drop in hormone production that occurs during menopause, that layer of protection goes away. Menopause also brings about other changes that increase heart disease risk, including higher blood pressure, raised triglycerides, and elevated LDL (bad) cholesterol. As a result, women become much more vulnerable to heart disease, heart attacks, sudden cardiac death, and other serious heart issues.

To add insult to injury, women often fare worse than men too. One of the biggest reasons is that they rarely experience the telltale chest and arm pain that men do when they have heart attacks—and they could have heart disease but remain symptom-free for years. This means so many women end up doing the worst possible thing when suffering a serious heart event…they do nothing.

If it’s hard to understand why, take a look at some of the most common symptoms of heart attack in women:

  • Shortness of breath
  • Weakness
  • Fatigue
  • Cold sweat
  • Dizziness
  • Nausea/indigestion/stomach pain
  • Feeling of weakness/heaviness in arms

While men certainly experience a number of these symptoms during a heart attack, it’s usually in addition to chest pain. In women, chest pain is often absent. Without this obvious sign of heart attack, many women dismiss their otherwise unremarkable symptoms as simple tiredness or overexertion.

The last thing I want any woman in the throes of a heart attack to do is nothing. Now that you know the signs and symptoms, you know what to look for. If something doesn’t feel right, call 911 immediately.

I also urge my female patients to take prevention seriously. As many as 2/3 of women who die of a heart issue had no symptoms and no idea there was an underlying problem in the first place.

One study out of Harvard showed just how crucial of a role lifestyle plays in preventing heart disease in women. They evaluated 20 years of data on nearly 70,000 women and found that 73 percent of cardiovascular disease cases could be attributed to poor lifestyle. However, adhering to six healthy habits—good diet, no smoking, healthy weight, regular exercise, minimal TV watching (seven hours or less per week), and limited alcohol (one or fewer drinks per day) reduced the risk of cardiovascular disease by a whopping 92 percent.

These lifestyle habits are important no matter what your age, but become even more critical post-menopause.


While heart disease is the biggest condition that presents itself differently in men and women, I would be remiss if I didn’t take a moment to discuss depression.

Depression has been a major topic in the news lately, due to the very unfortunate suicides of some well-known celebrities. While the vast majority of people who deal with depression don’t suffer the same fate (thankfully), research is finding that men and women do present some different symptom patterns. I want to share this with you so that you know what to look out for in yourself or your loved ones.

Overall, the core symptoms of depression that men and women experience are fairly similar. They include sadness, lack of motivation, sleep problems, loss of pleasure in once-beloved activities, and feelings of guilt and despair.

However, studies suggest that how men and women express many of these symptoms can vary. For example, women tend to convey their sadness outwardly, such as through crying or talking with friends, while men hold it in. As a result, men are more prone to intense outbursts of anger or violence than women.

Other characteristics of depression that are more common in men than women include:

  • Alcohol or drug abuse
  • Risky activity
  • “Escaping” by working late or spending excessive time away from “normal” life

Sadly, this is not surprising. In our culture, women are given permission to be vulnerable and open with their emotions, yet men are expected to be strong, silent, and stoic. It’s “normal” for a woman to cry, yet a man could be perceived as “weak” if he does the same. It’s certainly not fair, but these are the expectations we as a society place on men, and eventually, it can reach a head.

I will conclude by saying this: If you or a loved one (man, women, teen, child, or senior citizen alike) is experiencing any of these signs of depression, please seek help. Psychotherapy/counseling is extremely important and beneficial, and should be the basis of depression treatment. Additional therapies include exercise, various nutritional supplements, and even antidepressants. (While I don’t like these medications for long-term use, they can be helpful to restore balance.)

Whatever you do, don’t deal with depression alone.



Last Updated: August 16, 2018
Originally Published: June 19, 2018